Investigation On The Supersaturation And Precipitation Kinetics Of Weakly Basic Bcs Ii Drugs
Precipitation of solid drug particles in the gastro-intestinal tract affects both the rate and extent of intestinal drug absorption might be a factor that significantly contributes to the low and highly variable bioavailability observed for some low solubility drugs. A pre-requisite for such precipitation is that a super-saturated solution of the drug is formed within … Read more